You can bold the axis labels in Matplotlib with the following code. If you want to learn Python then I will highly recommend you to read This Book.
Bold Axis Labels
from matplotlib import pyplot as plt
a = [1,2,3,4,5]
b = [10,20,30,40,50]
plt.xlabel("Integers",fontweight='bold')
plt.ylabel("Multiple",fontweight='bold')
plt.plot(a,b)
plt.show()
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